A novel 4-dimensional live-cell imaging system to study leukocyte-endothelial dynamics in ANCA-associated vasculitis

• Main Authors: Catriona A. Walls (Author), Neil Basu (Author), Gayle Hutcheon (Author), Lars P. Erwig (Author), Mark A. Little (Author), Dana Kidder (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neutrophils, monocytes and the endothelium are critical to ANCA-associated vasculitis (AAV) pathogenesis. This study aimed to develop a 4-dimensional (4D) live-cell imaging system that would enable investigation of spatial and temporal dynamics of these cells in health and disease. We further aimed...