Syk Plays a Critical Role in the Expression and Activation of IRAK1 in LPS-Treated Macrophages

• Main Authors: Jae Gwang Park (Author), Young-Jin Son (Author), Byong Chul Yoo (Author), Woo Seok Yang (Author), Ji Hye Kim (Author), Jong-Hoon Kim (Author), Jae Youl Cho (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To address how interleukin-1 receptor-associated kinase 1 (IRAK1) is controlled by other enzymes activated by toll-like receptor (TLR) 4, we investigated the possibility that spleen tyrosine kinase (Syk), a protein tyrosine kinase that is activated at an earlier stage during TLR4 activation, plays a...