DR-5 and DLL-4 mAb Functionalized SLNs of Gamma-Secretase Inhibitors- An Approach for TNBC Treatment

• Main Authors: Mamta Kumari (Author), Praveen T. Krishnamurthy (Author), Sai kiran S. S. Pinduprolu (Author), Piyongsola Sola (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Triple-negative breast cancer (TNBC) is the most aggressive and heterogeneous cancer subtypes. High rates of metastasis, poor prognosis, and drug resistance are the major problems associated with TNBC. The current chemotherapeutics eliminate only the bulk tumor cells (non-BCSCs) and do not affect br...