Preclinical evaluation of a chemically detoxified pneumolysin as pneumococcal vaccine antigen
The use of protein antigens able to protect against the majority of Streptococcus pneumoniae serotypes is envisaged as stand-alone and/or complement to the current capsular polysaccharide-based pneumococcal vaccines. Pneumolysin (Ply) is a key virulence factor that is highly conserved in amino acid...
Saved in:
Main Authors: | Philippe Hermand (Author), Annick Vandercammen (Author), Emmanuel Mertens (Author), Emmanuel Di Paolo (Author), Vincent Verlant (Author), Philippe Denoël (Author), Fabrice Godfroid (Author) |
---|---|
Format: | Book |
Published: |
Taylor & Francis Group,
2017-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Genetically detoxified pertussis toxin induces superior antigen specific CD4 T cell responses compared to chemically detoxified pertussis toxin
by: Naveen Surendran, et al.
Published: (2019) -
Identification of SP1683 as a pneumococcal protein that is protective against nasopharyngeal colonization
by: Leen Moens, et al.
Published: (2018) -
Procoagulant Activity of Blood and Microvesicles Is Disturbed by Pneumococcal Pneumolysin, Which Interacts with Coagulation Factors
by: Sonja Oehmcke-Hecht, et al.
Published: (2022) -
Inhibition of Pneumolysin Cytotoxicity by Hydrolysable Tannins
by: Santeri Maatsola, et al.
Published: (2020) -
Glycyrol targets Pneumolysin (PLY) oligomerization to reduce Streptococcus pneumoniae toxicity
by: Yudi Li, et al.
Published: (2024)