2'-O-Galloylhyperin Isolated From Pyrola incarnata Fisch. Attenuates LPS-Induced Inflammatory Response by Activation of SIRT1/Nrf2 and Inhibition of the NF-κB Pathways in Vitro and Vivo

• Principais autores: Peng Wang (Autor), Chang Gao (Autor), Na Guo (Autor), Sun-Dong Zhang (Autor), Wei Wang (Autor), Li-Ping Yao (Autor), Jing Zhang (Autor), Thomas Efferth (Autor), Yu-Jie Fu (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2018-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

2'-O-galloylhyperin, a major compound of Pyrola incarnata Fisch., possesses a variety of biological and pharmacological activities, including anti-oxidative and anti-inflammatory activities. Nevertheless, the underlying molecular mechanisms of 2'-O-GH in microbial infection and sepsis are...