Combined Effect of Midazolam and Bone Morphogenetic Protein-2 for Differentiation Induction from C2C12 Myoblast Cells to Osteoblasts

• Main Authors: Yukihiko Hidaka (Author), Risako Chiba-Ohkuma (Author), Takeo Karakida (Author), Kazuo Onuma (Author), Ryuji Yamamoto (Author), Keiko Fujii-Abe (Author), Mari M. Saito (Author), Yasuo Yamakoshi (Author), Hiroshi Kawahara (Author)
• Format: Book
• Published: MDPI AG, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In drug repositioning research, a new concept in drug discovery and new therapeutic opportunities have been identified for existing drugs. Midazolam (MDZ) is an anesthetic inducer used for general anesthesia. Here, we demonstrate the combined effects of bone morphogenetic protein-2 (BMP-2) and MDZ o...