Zonisamide Attenuates MPTP Neurotoxicity in Marmosets

• Asıl Yazarlar: Mohammed Emamussalehin Choudhury (Yazar), Takashi Moritoyo (Yazar), Hayato Yabe (Yazar), Noriko Nishikawa (Yazar), Masahiro Nagai (Yazar), Madoka Kubo (Yazar), Seiji Matsuda (Yazar), Masahiro Nomoto (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2010-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract.: MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induces parkinsonism in humans and animals. The effects of zonisamide on dopamine neurons were studied in MPTP-treated common marmosets (Callithrix jacchus). Groups of animals (n = 3) were treated with MPTP (2.5 mg/kg, every 24 h × 3); M...