Niacin Inhibits Vascular Inflammation via Downregulating Nuclear Transcription Factor-κB Signaling Pathway

• Main Authors: Yanhong Si (Author), Ying Zhang (Author), Jilong Zhao (Author), Shoudong Guo (Author), Lei Zhai (Author), Shutong Yao (Author), Hui Sang (Author), Nana Yang (Author), Guohua Song (Author), Jue Gu (Author), Shucun Qin (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The study aimed to investigate the effect of niacin on vascular inflammatory lesions in vivo and in vitro as well as its lipid-regulating mechanism. In vivo study revealed that niacin downregulated the levels of inflammatory factors (IL-6 and TNF-α) in plasma, suppressed protein expression of CD68 a...