Selinexor and the Selective Inhibition of Nuclear Export: A New Perspective on the Treatment of Sarcomas and Other Solid and Non-Solid Tumors

• 主要な著者: Antonella Lucia Marretta (著者), Giuseppe Di Lorenzo (著者), Dario Ribera (著者), Lucia Cannella (著者), Claudia von Arx (著者), Alessandra Bracigliano (著者), Ottavia Clemente (著者), Roberto Tafuto (著者), Antonio Pizzolorusso (著者), Salvatore Tafuto (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Nucleocytoplasmic transport has been found dysregulated in many types of cancer and is often described as a poor prognostic factor. Specifically, Exportin-1 (XPO1) has been found overexpressed in many tumors and has become an attractive target in molecular oncology and therapeutics development. The...