Directed Fusion of Mesenchymal Stem Cells with Cardiomyocytes via VSV-G Facilitates Stem Cell Programming

• Main Authors: Nicholas A. Kouris (Author), Jeremy A. Schaefer (Author), Masato Hatta (Author), Brian T. Freeman (Author), Timothy J. Kamp (Author), Yoshihiro Kawaoka (Author), Brenda M. Ogle (Author)
• Format: Book
• Published: Hindawi Limited, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mesenchymal stem cells (MSCs) spontaneously fuse with somatic cells in vivo, albeit rarely, and the fusion products are capable of tissue-specific function (mature trait) or proliferation (immature trait), depending on the microenvironment. That stem cells can be programmed, or somatic cells reprogr...