Enhancing de novo ceramide synthesis induced by bisphenol A exposure aggravates metabolic derangement during obesity

• Main Authors: Gengfu Wang (Author), Xu Hong (Author), Jia Yu (Author), Yuheng Zhang (Author), Yuting Li (Author), Zuo Li (Author), Zhiyuan Zhu (Author), Shaoyun Yuan (Author), Xiaofei Zhang (Author), Sheng Wang (Author), Fuhai Zhu (Author), Yong Wang (Author), Changhao Wu (Author), Puyu Su (Author), Tong Shen (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Exposure to bisphenol A (BPA) has been shown to increase the prevalence of obesity and its related insulin resistance (IR). Ceramide is a sphingolipid known to facilitate the production of proinflammatory cytokines and subsequently exacerbate inflammation and IR during the progression of...