Treating cachexia using soluble ACVR2B improves survival, alters mTOR localization, and attenuates liver and spleen responses

Abstract Background Cancer cachexia increases morbidity and mortality, and blocking of activin receptor ligands has improved survival in experimental cancer. However, the underlying mechanisms have not yet been fully uncovered. Methods The effects of blocking activin receptor type 2 (ACVR2) ligands...

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Main Authors: Tuuli A. Nissinen (Author), Jaakko Hentilä (Author), Fabio Penna (Author), Anita Lampinen (Author), Juulia H. Lautaoja (Author), Vasco Fachada (Author), Tanja Holopainen (Author), Olli Ritvos (Author), Riikka Kivelä (Author), Juha J. Hulmi (Author)
Format: Book
Published: Wiley, 2018-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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