Intranasally Administered L-Myc-Immortalized Human Neural Stem Cells Migrate to Primary and Distal Sites of Damage after Cortical Impact and Enhance Spatial Learning

• Main Authors: Margarita Gutova (Author), Jeffrey P. Cheng (Author), Vikram Adhikarla (Author), Lusine Tsaturyan (Author), Michael E. Barish (Author), Russell C. Rockne (Author), Eleni H. Moschonas (Author), Corina O. Bondi (Author), Anthony E. Kline (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As the success of stem cell-based therapies is contingent on efficient cell delivery to damaged areas, neural stem cells (NSCs) have promising therapeutic potential because they inherently migrate to sites of central nervous system (CNS) damage. To explore the possibility of NSC-based therapy after...