A New Class of PSMA-617-Based Hybrid Molecules for Preoperative Imaging and Intraoperative Fluorescence Navigation of Prostate Cancer

• Main Authors: Ann-Christin Eder (Author), Jessica Matthias (Author), Martin Schäfer (Author), Jana Schmidt (Author), Nils Steinacker (Author), Ulrike Bauder-Wüst (Author), Lisa-Charlotte Domogalla (Author), Mareike Roscher (Author), Uwe Haberkorn (Author), Matthias Eder (Author), Klaus Kopka (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The development of PSMA-targeting low-molecular-weight hybrid molecules aims at advancing preoperative imaging and accurate intraoperative fluorescence guidance for improved diagnosis and therapy of prostate cancer. In hybrid probe design, the major challenge is the introduction of a bulky dye to pe...