Cigarette smoke exposure induces ROS-mediated autophagy by regulating sestrin, AMPK, and mTOR level in mice

• Hlavní autoři: Ana Lucia Bernardo Carvalho Morsch (Autor), Elvis Wisniewski (Autor), Thais Fernandes Luciano (Autor), Vitor Hugo Comin (Autor), Gustavo de Bem Silveira (Autor), Scherolin de Oliveira Marques (Autor), Anand Thirupathi (Autor), Paulo Cesar Silveira Lock (Autor), Claudio Teodoro De Souza (Autor)
• Médium: Kniha
• Vydáno: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Many pathological conditions linked to cigarette smoking are caused by the production of reactive oxygen species (ROS). The present study was conducted to analyze the effect of ROS on the lungs of Swiss mice exposed to cigarette smoking, focusing on autophagy-mediated mechanisms, and investigate the...