Unveiling the Relationship between Ceftobiprole and High-Molecular-Mass (HMM) Penicillin-Binding Proteins (PBPs) in <i>Enterococcus faecalis</i>

Unveiling the Relationship between Ceftobiprole and High-Molecular-Mass (HMM) Penicillin-Binding Proteins (PBPs) in <i>Enterococcus faecalis</i>

Low-affinity PBP4, historically linked to penicillin resistance in <i>Enterococcus faecalis</i>, may still have affinity for novel cephalosporins. Ceftobiprole (BPR) is a common therapeutic choice, even with PBP4-related overexpression and amino acid substitution due to mutations. Our st...

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Main Authors: Paola Conti (Author), Lorenzo Mattia Lazzaro (Author), Fabio Longo (Author), Federica Lenzo (Author), Alessandra Giardina (Author), Sebastiano Alberto Fortuna (Author), Stefania Stefani (Author), Floriana Campanile (Author)
Format: Book
Published: MDPI AG, 2024-01-01T00:00:00Z.
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3rd Floor Main Library

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