Dynamics of Onchocerca volvulus microfilarial densities after ivermectin treatment in an ivermectin-naïve and a multiply treated population from Cameroon.

• Main Authors: Sébastien D S Pion (Author), Hugues C Nana-Djeunga (Author), Joseph Kamgno (Author), Nicholas Tendongfor (Author), Samuel Wanji (Author), Flobert Njiokou (Author), Roger K Prichard (Author), Michel Boussinesq (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND/OBJECTIVE: Ivermectin has been the keystone of onchocerciasis control for the last 25 years. Sub-optimal responses to the drug have been reported in Ghanaian communities under long-term treatment. We assessed, in two Cameroonian foci, whether the microfilaricidal and/or embryostatic effec...