Antagonism of Cerebral High Mobility Group Box 1 Ameliorates Dendritic Cell Dysfunction in Sepsis

• Main Authors: Chao Ren (Author), Ren-qi Yao (Author), Li-xue Wang (Author), Jun-cong Li (Author), Kun-wei Chen (Author), Yao Wu (Author), Ning Dong (Author), Yong-wen Feng (Author), Yong-ming Yao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sepsis has emerged as a global health issue, and accounts for millions of deaths in intensive care units. Dysregulation of the immune response reportedly contributes to the pathogenesis and progression of this lethal condition, which involves both the dysfunction of immune cells and incompetent immu...