Syndecan-1 (CD138) immunohistochemical expression patterns in lupus nephritis; reflections on different clinicopathological parameters

• Autori principali: Marwa M Shakweer (Autore), Lobna S Shash (Autore)
• Natura: Libro
• Pubblicazione: Society of Diabetic Nephropathy Prevention, 2021-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Introduction: Syndecan 1 (SCD1) is a lectin expressed at the surface of renal tubular epithelial cells and plasma cells. In epithelial cells, cell surface syndecan1 is cleaved by inflammation-induced proteases (eg, ADAMTS, MMP), since loss of cell surface syndecan1 is associated with higher suscepti...