The albumin-exendin-4 recombinant protein E2HSA improves glycemic control and β-cell function in spontaneous diabetic KKAy mice

• Główni autorzy: Caina Li (Autor), Shaocong Hou (Autor), Shuainan Liu (Autor), Yi Huan (Autor), Sujuan Sun (Autor), Quan Liu (Autor), Zhufang Shen (Autor)
• Format: Książka
• Wydane: BMC, 2017-06-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Background E2HSA is a genetic fusion protein that consists of two tandem exendin-4 molecules that are covalently bonded to recombinant human serum albumin via a peptide linker. Previous studies have demonstrated that E2HSA significantly decreased blood glucose levels, improved β-cell functi...