The albumin-exendin-4 recombinant protein E2HSA improves glycemic control and β-cell function in spontaneous diabetic KKAy mice

• Автори: Caina Li (Автор), Shaocong Hou (Автор), Shuainan Liu (Автор), Yi Huan (Автор), Sujuan Sun (Автор), Quan Liu (Автор), Zhufang Shen (Автор)
• Формат: Книга
• Опубліковано: BMC, 2017-06-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Background E2HSA is a genetic fusion protein that consists of two tandem exendin-4 molecules that are covalently bonded to recombinant human serum albumin via a peptide linker. Previous studies have demonstrated that E2HSA significantly decreased blood glucose levels, improved β-cell functi...