A Bitter Taste Receptor as a Novel Molecular Target on Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma

• Main Authors: Jessica Hung (Author), Samantha M. Perez (Author), Siva Sai Krishna Dasa (Author), Sarah P. Hall (Author), Danielle B. Heckert (Author), Brian P. Murphy (Author), Howard C. Crawford (Author), Kimberly A. Kelly (Author), Lindsey T. Brinton (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer-associated fibroblasts (CAFs) execute diverse and complex functions in cancer progression. While reprogramming the crosstalk between CAFs and cancer epithelial cells is a promising avenue to evade the adverse effects of stromal depletion, drugs are limited by their suboptimal pharmacokinetics...