A New Approach for Preparing Stable High-Concentration Peptide Nanoparticle Formulations

• Main Authors: Chloe Hu (Author), Nanzhi Zang (Author), Yu Tong Tam (Author), Desmond Dizon (Author), Kaylee Lee (Author), Jodie Pang (Author), Elizabeth Torres (Author), Yusi Cui (Author), Chun-Wan Yen (Author), Dennis H. Leung (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The subcutaneous administration of therapeutic peptides would provide significant benefits to patients. However, subcutaneous injections are limited in dosing volume, potentially resulting in high peptide concentrations that can incur significant challenges with solubility limitations, high viscosit...