Neuroprotective and Antiapoptotic Activity of Lineage-Negative Bone Marrow Cells after Intravitreal Injection in a Mouse Model of Acute Retinal Injury

• Main Authors: Anna Machalińska (Author), Dorota Rogińska (Author), Ewa Pius-Sadowska (Author), Miłosz P. Kawa (Author), Edyta Paczkowska (Author), Michał Rudnicki (Author), Renata Lejkowska (Author), Bartłomiej Baumert (Author), Barbara Wiszniewska (Author), Bogusław Machaliński (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We investigated effects of bone marrow-derived, lineage-negative cell (Lin−BMC) transplantation in acute retinal injury. Lin−BMCs were intravitreally injected into murine eyes at 24 h after NaIO3-induced injury. Morphology, function, and expression of apoptosis-related genes, including brain-derived...