Short-term Weight Trajectory of Severely Obese Individuals With and Without Pathogenic Satiety-Regulation Melanocortin 3/4 Receptor (MC3/4R) Mutations From a Multi-ethnic Asian Large Bariatric Surgery Program

• Main Authors: Joel Guanyi Lim GCE A-levels (Author), Angela Moh PhD (Author), Bhuvaneswari Pandian BSc (Author), Chalani Udhyami Ubeynarayana MSc (Author), Nathaniel Guanning Lim GCE A-levels (Author), Bo Chuan Tan MD, MRCS, MMed (Author), Deborah Ng MBBS, MRCS, MMed (Author), Tavintharan Subramaniam MBBS, MRCP, MCI (Author), Anton Cheng MBBS, FRACS (Author), Su Chi Lim MBBS, MRCP, PhD (Author)
• Format: Book
• Published: SAGE Publishing, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The melanocortin (3 or 4) receptor (MC3/4R) is involved in regulating satiety and body weight. Therefore, pathogenic mutation in MC3/4R is associated with severe obesity, for which bariatric surgery is one of the treatment options. However, there is limited data on whether individuals with MC3/4R mu...