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LC-MS/MS method for the quantitation of serum tocilizumab in rheumatoid arthritis patients using rapid tryptic digestion without IgG purification

The quantitation of serum tocilizumab using liquid chromatography tandem-mass spectrometry (LC-MS/MS) method has not been widely applied in clinical settings because of its time-consuming and costly sample pretreatments. The present study aimed to develop a validated LC-MS/MS method for detecting se...

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Bibliographic Details
Main Authors:	Takashi Mochizuki (Author), Kaito Shibata (Author), Takafumi Naito (Author), Kumiko Shimoyama (Author), Noriyoshi Ogawa (Author), Masato Maekawa (Author), Junichi Kawakami (Author)
Format:	Book
Published:	Elsevier, 2022-12-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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