Heterogeneity of weight loss and transcriptomic signatures in pancreatic ductal adenocarcinoma

• Main Authors: Andrea N. Riner (Author), Kelly M. Herremans (Author), Vignesh Vudatha (Author), Song Han (Author), Xufeng Qu (Author), Jinze Liu (Author), Nitai Mukhopadhyay (Author), Devon C. Freudenberger (Author), Thomas J. George (Author), Sarah M. Judge (Author), Andrew R. Judge (Author), Steven J. Hughes (Author), Jose G. Trevino (Author)
• Format: Book
• Published: Wiley, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is highly associated with cachexia and weight loss, which is driven by the tumour's effect on the body. Data are lacking on differences in these metrics based on PDAC anatomic location. We hypothesize that the primary tumour's ana...