LigB subunit vaccine confers sterile immunity against challenge in the hamster model of leptospirosis.

• Main Authors: Neida L Conrad (Author), Flávia W Cruz McBride (Author), Jéssica D Souza (Author), Marcelle M Silveira (Author), Samuel Félix (Author), Karla S Mendonça (Author), Cleiton S Santos (Author), Daniel A Athanazio (Author), Marco A Medeiros (Author), Mitermayer G Reis (Author), Odir A Dellagostin (Author), Alan J A McBride (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neglected tropical diseases, including zoonoses such as leptospirosis, have a major impact on rural and poor urban communities, particularly in developing countries. This has led to major investment in antipoverty vaccines that focus on diseases that influence public health and thereby productivity....