Gentamicin-Ascorbic Acid Encapsulated in Chitosan Nanoparticles Improved In Vitro Antimicrobial Activity and Minimized Cytotoxicity

• Main Authors: Mohamed A. Abdel-Hakeem (Author), Ahmed I. Abdel Maksoud (Author), Mohammed Abdullah Aladhadh (Author), Khalid Abdulrahman Almuryif (Author), Rafaat M. Elsanhoty (Author), Dalia Elebeedy (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nano-drug delivery is a promising tactic to enhance the activity and minimize the cytotoxicity of antimicrobial drugs. In the current study, chitosan nanoparticles (CSNPs) were used as a carrier for the delivery of gentamicin sulfate (GM) and ascorbic acid (AA). The particles were synthesized by ion...