Functional Analysis of a Novel Complement C5a Receptor 1-Blocking Monoclonal Antibody
Introduction: The complement system anaphylatoxin C5a is a critical player in inflammation. By binding to complement C5a receptor 1 (C5aR1/CD88), C5a regulates many cellular functions, mainly as a potent pro-inflammatory inducer. We describe the generation and selection of a potent antagonistic C5aR...
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Karger Publishers,
2023-11-01T00:00:00Z.
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A1234.567 |
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