Functional Analysis of a Novel Complement C5a Receptor 1-Blocking Monoclonal Antibody

Introduction: The complement system anaphylatoxin C5a is a critical player in inflammation. By binding to complement C5a receptor 1 (C5aR1/CD88), C5a regulates many cellular functions, mainly as a potent pro-inflammatory inducer. We describe the generation and selection of a potent antagonistic C5aR...

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Main Authors: Leon Cyranka (Author), Ida Mariegaard (Author), Mikkel-Ole Skjødt (Author), Rafael Bayarri-Olmos (Author), Tom Eirik Mollnes (Author), Peter Garred (Author), Anne Rosbjerg (Author)
Format: Book
Published: Karger Publishers, 2023-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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