Clinical Management of COVID-19 in Cancer Patients with the STAT3 Inhibitor Silibinin

• Main Authors: Joaquim Bosch-Barrera (Author), Ariadna Roqué (Author), Eduard Teixidor (Author), Maria Carmen Carmona-Garcia (Author), Aina Arbusà (Author), Joan Brunet (Author), Begoña Martin-Castillo (Author), Elisabet Cuyàs (Author), Sara Verdura (Author), Javier A. Menendez (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

COVID-19 pathophysiology is caused by a cascade of respiratory and multiorgan failures arising, at least in part, from the SARS-CoV-2-driven dysregulation of the master transcriptional factor STAT3. Pharmacological correction of STAT3 over-stimulation, which is at the root of acute respiratory distr...