Development of Dual-Targeted Mixed Micelles Loaded with Celastrol and Evaluation on Triple-Negative Breast Cancer Therapy

• Autors principals: Siying Huang (Autor), Simeng Xiao (Autor), Xuehao Li (Autor), Ranran Tao (Autor), Zhangwei Yang (Autor), Ziwei Gao (Autor), Junjie Hu (Autor), Yan Meng (Autor), Guohua Zheng (Autor), Xinyan Chen (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2024-09-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Considering that the precise delivery of Celastrol (Cst) into mitochondria to induce mitochondrial dysfunction may be a potential approach to improve the therapeutic outcomes of Cst on TNBC, a novel tumor mitochondria dual-targeted mixed-micelle nano-system was fabricated via self-synthesized triphe...