Development of Dual-Targeted Mixed Micelles Loaded with Celastrol and Evaluation on Triple-Negative Breast Cancer Therapy

• Main Authors: Siying Huang (Author), Simeng Xiao (Author), Xuehao Li (Author), Ranran Tao (Author), Zhangwei Yang (Author), Ziwei Gao (Author), Junjie Hu (Author), Yan Meng (Author), Guohua Zheng (Author), Xinyan Chen (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Considering that the precise delivery of Celastrol (Cst) into mitochondria to induce mitochondrial dysfunction may be a potential approach to improve the therapeutic outcomes of Cst on TNBC, a novel tumor mitochondria dual-targeted mixed-micelle nano-system was fabricated via self-synthesized triphe...