Pharmacogenetics Based Dose Prediction Model for Initial Tacrolimus Dosing in Renal Transplant Recipients

• Principais autores: Lekshmy Srinivas (Autor), Noble Gracious (Autor), Radhakrishnan R. Nair (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Tacrolimus, an immunosuppressant used in solid organ transplantation, has a narrow therapeutic index and exhibits inter-individual pharmacokinetic variability. Achieving and maintaining a therapeutic level of the drug by giving appropriate doses is crucial for successful immunosuppression, especiall...