In vitro and in vivo evaluation of liposomes modified with polypeptides and red cell membrane as a novel drug delivery system for myocardium targeting

• Main Authors: Xueyan Liu (Author), Liangke Zhang (Author), Wengao Jiang (Author), Zhangyou Yang (Author), Zongjie Gan (Author), Chao Yu (Author), Ran Tao (Author), Huali Chen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ischemic cardiac disease (ICD) is a cardiovascular disease with high morbidity and mortality. In this study, a novel myocardial targeted drug delivery system was developed represented by co-modified liposomes consisting of red cell membrane (RCM), and the peptides TAT and PCM. Liposomes were prepare...