Preparation and evaluation of duloxetine hydrochloride enteric-coated pellets with different enteric polymers

• Main Authors: Chen Kuang (Author), Yinghua Sun (Author), Bing Li (Author), Rui Fan (Author), Jing Zhang (Author), Yumin Yao (Author), Zhonggui He (Author)
• Format: Book
• Published: Elsevier, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The main purpose of the present study was to prepare duloxetine hydrochloride (DXH) enteric-coated pellets using different enteric polymers. Three layers (drug-loaded layer, barrier layer, and enteric-coated layer) were applied to the inert core pellets, successively. The optimal formulation was man...