Randomized single-blinded non-inferiority trial of 7 mg/kg pentamidine isethionate versus 4 mg/kg pentamidine isethionate for cutaneous leishmaniaisis in Suriname.

• Main Authors: Ricardo V P F Hu (Author), Masja Straetemans (Author), Alida D Kent (Author), Leslie O A Sabajo (Author), Henry J C de Vries (Author), Rudy F M Lai A Fat (Author)
• 格式: 图书
• 出版: Public Library of Science (PLoS), 2015-03-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Standard treatment of cutaneous leishmaniasis (CL) in Suriname entails three injections of pentamidine isethionate (PI) 4 mg/kg per injection in 7 days (7 day regimen). Compliance to treatment is low and may contribute to increasing therapy failure. A 3 day regimen, including 2 injections of 7 mg/kg...