D-4F decreases the expression of Aβ protein through up-regulating long non coding RNA sirt1-as in SAMP8 mice

• Main Authors: Xiao-Han Ding (Author), Jie Han (Author), Yuan Liu (Author), Ying Jin (Author), Ping Ye (Author)
• 格式: 图书
• 出版: Elsevier, 2017-05-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Background and objective: Cholesterol plays key roles on (Aβ) metabolism and production. D-4F is the apolipoprotein A-I mimetic peptide which has been revealed a critical role in regulation cholesterol. We aimed at identifying the effects of D-4F on Aβ production in SAMP8 and the underlying mechanis...