Comparison of Regenerative Tissue Quality following Matrix-Associated Cell Implantation Using Amplified Chondrocytes Compared to Synovium-Derived Stem Cells in a Rabbit Model for Cartilage Lesions

• Main Authors: Hagen Schmal (Author), Justyna M. Kowal (Author), Moustapha Kassem (Author), Michael Seidenstuecker (Author), Anke Bernstein (Author), Katharina Böttiger (Author), Tanshiyue Xiong (Author), Norbert P. Südkamp (Author), Eva J. Kubosch (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Known problems of the autologous chondrocyte implantation motivate the search for cellular alternatives. The aim of the study was to test the potential of synovium-derived stem cells (SMSC) to regenerate cartilage using a matrix-associated implantation. In an osteochondral defect model of the medial...