TGFβ1 pathway components in breast cancer tissue from aggressive subtypes correlate with better prognostic parameters in ER-positive and p53-negative cancers

• Main Authors: Glauco Akelinghton Freire Vitiello (Author), Marla Karine Amarante (Author), Jefferson Crespigio (Author), Bruna Karina Banin Hirata (Author), Nathalia de Sousa Pereira (Author), Karen Brajão de Oliveira (Author), Roberta Losi Guembarovski (Author), Maria Angelica Ehara Watanabe (Author)
• Format: Book
• Published: BMC, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background TGFβ signaling exerts context-specific effects in breast cancer (BC) pathogenesis and single nucleotide polymorphisms (SNPs) in TGFβ-signaling components play a role in the genetic control of their expression and in BC susceptibility and clinical presentation. However, studies in...