In Vitro-In Vivo Correlations (IVIVC) for Predicting the Clinical Performance of Metronidazole Topical Creams Intended for Local Action

• Main Authors: Seeprarani Rath (Author), Isadore Kanfer (Author)
• 格式: 图书
• 出版: MDPI AG, 2023-01-01T00:00:00Z.
• 主题: article
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The safety and efficacy of a generic medicine can be confirmed by demonstrating bioequivalence (BE) between the generic product and its reference listed drug (RLD) by measuring drug concentrations in the blood following administration. However, for topical dermatological products that are not absorb...