Overexpression of c-<it>erb</it>B2 is a negative prognostic factor in anaplastic astrocytomas

• Main Authors: Gulati Michel (Author), Granli Unn S (Author), Ytterhus Borgny (Author), Gulati Sasha (Author), Lydersen Stian (Author), Torp Sverre H (Author)
• Format: Book
• Published: BMC, 2010-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>The epidermal growth factor receptor (EGFR) family, consisting of four tyrosine kinase receptors, c-<it>erb</it>B1-4, seems to be influential in gliomagenesis. The aim of this study was to investigate EGFR gene amplification and expression of c-<it...