Leveraging mathematical modeling to analyze nonadherence for hydroxyurea therapy in sickle cell disease

Abstract Nonadherence is common in individuals with sickle cell disease (SCD) on hydroxyurea therapy and can be observed with waning improvements in hematologic parameters or biomarkers like mean cell volume and fetal hemoglobin level over time. We modeled the impact of hydroxyurea nonadherence on l...

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Main Authors: Akancha Pandey (Author), Rubesh Raja (Author), Jeremie H. Estepp (Author), Doraiswami Ramkrishna (Author)
Format: Book
Published: Wiley, 2023-06-01T00:00:00Z.
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