Meganuclease targeting HSV-1 protects against herpetic keratitis: Application to corneal transplants

Meganuclease targeting HSV-1 protects against herpetic keratitis: Application to corneal transplants

Herpes simplex virus (HSV) infection is a leading cause of corneal blindness. However, keratoplasty is only rarely proposed due to the high frequency of graft failure and associated recurrences. Gene therapy of the corneal graft might provide sustained protection against HSV infection. To test that...

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Main Authors: Benoit Chapellier (Author), Damien Guindolet (Author), Daniel Pereira (Author), Roman Galetto (Author), José-Alain Sahel (Author), Marc Labetoulle (Author), Eric E. Gabison (Author)
Format: Book
Published: Elsevier, 2022-12-01T00:00:00Z.
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