Doxycycline-Eluting Core-Shell Type Nanofiber-Covered Trachea Stent for Inhibition of Cellular Metalloproteinase and Its Related Fibrotic Stenosis

• Glavni autori: Rengarajan Baskaran (Autor), Un-Jeong Ko (Autor), Enkhzaya Davaa (Autor), Ji Eun Park (Autor), Yixin Jiang (Autor), Junghan Lee (Autor), Su-Geun Yang (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2019-08-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

In this study, we fabricated a doxycycline (doxy)-eluting nanofiber-covered endotracheal stent for the prevention of stent intubation-related tissue fibrosis and re-stenosis. The nanofiber was deposited directly on the outer surface of the stent using a coaxial electrospinning method to form a doxy-...