MiR-19a-3p Suppresses M1 Macrophage Polarization by Inhibiting STAT1/IRF1 Pathway

• Main Authors: Xiaoxiao Zhu (Author), Qiang Guo (Author), Jing Zou (Author), Bin Wang (Author), Zhen Zhang (Author), Ran Wei (Author), Lin Zhao (Author), Yunhong Zhang (Author), Chu Chu (Author), Xiaoxiao Fu (Author), Xia Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrophages, an important type of immune cells, are generally polarized to classically activated macrophage (M1) or alternatively activated macrophage (M2) to respond to environmental stimuli. Signal transducer and activator of transcription 1 (STAT1), a very important transcription factor, can prom...