Cannabidiol in Pharmacoresistant Epilepsy: Clinical Pharmacokinetic Data From an Expanded Access Program

• Main Authors: Manuela Contin (Author), Susan Mohamed (Author), Margherita Santucci (Author), Monica Anna Maria Lodi (Author), Emilio Russo (Author), Oriano Mecarelli (Author), CBD LICE Italy Study Group (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Aim: Data on the clinical pharmacokinetics of cannabidiol (CBD) are scanty. We explored the effect of demographic and clinical variables on plasma concentrations of purified CBD in patients with Dravet (DS) and Lennox-Gastaut syndrome (LGS).Methods: The study design was an open, prosp...