Lig-8, a Bioactive Lignophenol Derivative From Bamboo Lignin, Protects Against Neuronal Damage In Vitro and In Vivo

• Main Authors: Yasushi Ito (Author), Masamitsu Shimazawa (Author), Yukihiro Akao (Author), Yoshimi Nakajima (Author), Norio Seki (Author), Yoshinori Nozawa (Author), Hideaki Hara (Author)
• Format: Book
• Published: Elsevier, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lig-8, a lignophenol derivative from bamboo lignin, potently suppresses oxidative stress-induced apoptosis. Here, we first examined in vitro whether lig-8 protects against neuronal damage induced by oxygen-glucose deprivation (OGD) followed by reoxygenation, tunicamycin [endoplasmic reticulum (ER)-s...