NLRP3 inflammasome activation by Paracoccidioides brasiliensis.

• Main Authors: Aldo Henrique Tavares (Author), Kelly Grace Magalhães (Author), Raquel Das Neves Almeida (Author), Rafael Correa (Author), Pedro Henrique Burgel (Author), Anamélia Lorenzetti Bocca (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Paracoccidioides brasiliensis is the etiologic agent of paracoccidioidomycosis (PCM), the most prevalent systemic mycosis that is geographically confined to Latin America. The pro-inflammatory cytokine IL-1β that is mainly derived from the activation of the cytoplasmic multiprotein complex inflammas...