KLK5 induces shedding of DPP4 from circulatory Th17 cells in type 2 diabetes

KLK5 induces shedding of DPP4 from circulatory Th17 cells in type 2 diabetes

Objective: Increasing plasma levels and activity of dipeptidyl peptidase-4 (DPP4 or CD26) are associated with rapid progression of metabolic syndrome to overt type 2 diabetes mellitus (T2DM). While DPP4 inhibitors are increasingly used as anti-hyperglycemic agents, the reason for the increase in pla...

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Main Authors: Titli Nargis (Author), Krishna Kumar (Author), Amrit Raj Ghosh (Author), Amit Sharma (Author), Dipayan Rudra (Author), Debrup Sen (Author), Saikat Chakrabarti (Author), Satinath Mukhopadhyay (Author), Dipyaman Ganguly (Author), Partha Chakrabarti (Author)
Format: Book
Published: Elsevier, 2017-11-01T00:00:00Z.
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