Haptoglobin Genotype-Dependent Anti-Inflammatory Signaling in CD163+ Macrophages
Intraplaque hemorrhage causes adaptive remodelling of macrophages towards a protective phenotype specialized towards handling iron and lipid overload, denoted Mhem. The Mhem phenotype expresses elevated levels of hemoglobin (Hb) scavenger receptor, CD163, capable of endocytosing pro-oxidant free Hb...
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Main Authors: | R. Clive Landis (Author), Pandelis Philippidis (Author), Jan Domin (Author), Joseph J. Boyle (Author), Dorian O. Haskard (Author) |
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Format: | Book |
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Hindawi Limited,
2013-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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