Relationship of hemoglobin level and plasma coproporphyrin‐I concentrations as an endogenous probe for phenotyping OATP1B

• Main Authors: Yosuke Suzuki (Author), Yuri Sasamoto (Author), Teruhide Koyama (Author), Chisato Yoshijima (Author), Ayako Oda (Author), Masahiro Nakatochi (Author), Michiaki Kubo (Author), Yukihide Momozawa (Author), Ritei Uehara (Author), Keiko Ohno (Author)
• Format: Book
• Published: Wiley, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Plasma coproporphyrin‐I (CP‐I) concentration is used as a sensitive and selective endogenous probe for phenotyping organic anion transporting polypeptides 1B (OATP1B) activity in many studies. CP‐I is produced in the process of heme synthesis, but the relationship between plasma CP‐I concen...